LAST UPDATED MAR 12, 2026
/hrt/feminizing/estradiol-valerate

Estradiol Valerate

[estradiol]
Rev: 2025.12
Summary
Injectable estrogen ester, typically injected every 5-7 days

DESCRIPTION

Estradiol Valerate (EV) is an esterified form of estradiol commonly used for intramuscular or subcutaneous injection. The valerate ester slows release from the injection site, allowing for less frequent dosing. It has a half-life of approximately 4-5 days.

DOSING GUIDELINES

RouteDose RangeFrequencyTarget Levels
Injection (IM)4mg10mgEvery 5-7 days150+ pg/mL at trough

DETAILED NOTES

Injection (IM)

Low half-life ester.

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Rev: 2025.12hrt.fm